Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova, Clemens Mayer, Mirjana Efremova, Dietmar Rieder, Hubert Hackl, Zlatko Trajanoski
2017 Cell Reports  
We have recently developed an analytical strategy to characterize the cellular composition of the immune infiltrates and examined colorectal cancer (CRC) datasets from the TCGA (Angelova et al., 2015) . Our approach is based on the use of metagenes, i.e. non-overlapping sets of genes that are . CC-BY 4.0 International license not peer-reviewed) is the author/funder. It is made available under a
doi:10.1016/j.celrep.2016.12.019 pmid:28052254 fatcat:ixpdydpn5neo7nxmwck7jfpgi4