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The presence of a renln-angiotensin system in the central nervous system (CNS) has been demonstrated by several investigators, but little is known regarding the origin of its components. In this study we have compared the immunological and physical-chemical nature of angiotensinogen in plasma and cerebrospinal fluid (CSF) of human subjects and explored whether differences are present in CSF angiotensinogen concentrations of normal and hypertensive subjects. No significant differences in thedoi:10.1161/01.hyp.2.4.432 pmid:7399627 fatcat:3rfllnhvcjeuhbmmudwkunctum