Use of Japanese Quail Embryo Fibroblast Cells for Propagation and Assay of Turkey Herpesvirus FC-1261

W. M. Colwell, D. G. Simmons, K. E. Muse
1974 Applied microbiology  
Japanese quail (Coturnix coturnix japonica) fibroblast cell culture monolayers were found to provide a very satisfactory system in which to propagate and assay turkey herpesvirus FC-126, which is used for production of Marek's disease vaccine. Japanese quail cells were more sensitive than duck cells and of approximately equal sensitivity to chicken cells. Foci of infection developed rapidly and uniformly, were of larger size, and were more easily discernible in quail cells than in chicken cells.
doi:10.1128/aem.27.1.218-223.1974 fatcat:3f5mn2b3cjgsfczxlwhvh2zhru