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Pathophysiology of Atherothrombosis — Thrombus Growth, Vascular Thrombogenicity, and Plaque Metabolism
[chapter]
2015
Thrombosis, Atherosclerosis and Atherothrombosis - New Insights and Experimental Protocols
Atherosclerotic plaque disruption does not always result in acute symptomatic events. Therefore, the formation of a large thrombus is a critical step in the development of atherothrombosis. However, little is known about the mechanisms involved in thrombus growth processes after plaque disruption. Studies in vivo have demonstrated that the tissue factor (TF) derived from the vascular wall contributes to the formation of thrombindependent platelet-fibrin thrombus on atherosclerotic arteries but
doi:10.5772/61769
fatcat:mrss2w7dsfgszexlhtda2ks6cy