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Thymus Degeneration and Regeneration
2021
Frontiers in Immunology
The immune system's ability to resist the invasion of foreign pathogens and the tolerance to self-antigens are primarily centered on the efficient functions of the various subsets of T lymphocytes. As the primary organ of thymopoiesis, the thymus performs a crucial role in generating a self-tolerant but diverse repertoire of T cell receptors and peripheral T cell pool, with the capacity to recognize a wide variety of antigens and for the surveillance of malignancies. However, cells in the
doi:10.3389/fimmu.2021.706244
pmid:34539637
pmcid:PMC8442952
fatcat:wa7tvc7tsbeqxfig5irni6frpm