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Real-world Evidence of Diagnostic Testing and Treatment Patterns in U.S. Breast Cancer Patients with Implications for Treatment Biomarkers from RNA-sequencing Data
INTRODUCTION We performed a retrospective analysis of longitudinal real-world data (RWD) from breast cancer patients to replicate results from clinical studies and demonstrate the feasibility of generating real-world evidence. We also assessed the value of transcriptome profiling as a complementary tool for determining molecular subtypes. PATIENTS AND METHODS De-identified, longitudinal data were analyzed after abstraction from U.S. breast cancer patient records structured and stored in thedoi:10.1101/2020.08.07.20168401 fatcat:i5esthyfgzhopb7hbdpbjphin4