S4. Neuropathlogy of Circulatory Disturbances. In Particular of Ischemic Process

Hirotsugu SHIRAKI
1964 Neurologia medico-chirurgica  
When the administration of KCN caused the 02 supplies to suffice for the brain, the cerebral blood flows became to increase and decrease , responding to rising and falling of rather the blood pressures than the cerebrospinal fluid pressures, that is to say, when cerebral tissues became to be made histotoxic, the push-pull relation between changes of the cerebral blood flow and the cerebrospinal fluid pressure disappeared . Especially in the thalamic region, this push-pull relation tended to
more » ... ppear in the restoring course of the cerebral tissue 02 tension after anoxic anoxia, more remarkably when glucose was administered previously. This fact seemed to suggest that in the thalamus the metabolic rate must be mainly dependent upon the glycolytic reactions which are not consuming so much oxygen and also not so fast as the oxidative reactions predominant in the cortex. 3) It seemed expectedly that the various wave-forms of the EEG in the dog brain, especially suffering from anoxia, could be illustrated significantly to some extent, according to the circulatory and the metabolic characteristics of the various cerebral regions as mentioned.
doi:10.2176/nmc.6.193b fatcat:unzssb3fovgqjpyjqvzcql37zy