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Many radiotherapy centers don't pay attention to effect of ionization champers type on accuracy of quality control measurements. They use any available ionization champers in all quality control and data entry measurements (1,2) . Many studies were carried out in this field to compare different ionization champers in small fields but large fields were not completely compared before (3.4). The aim of this work is to compare output factor in large field using two different sizes ionizationdoi:10.24297/jap.v13i5.6134 fatcat:5wmkax3vcvfyvoga2vqz5jqxya