Gender dependent gut microbiome in obese Egyptian individuals

Mohammed Ali
2019 Records of Pharmaceutical and Biomedical Sciences  
The majority of human microbiota resides in the GIT approximately 3.6 x 10 13 . Identification of gut microbiota composition in obese individuals and defining bacterial community differences between men and females help in the treatment of certain metabolic disorders. Gut microbiome analysis of men and females was performed with 16s rRNA genes using Illumina MiSeq sequencing. 5 stool samples for each group were collected from obese men and women. In our study, we found that bacterial
more » ... acterial communities of men were more diverse in comparison to women. Firmicutes /Bacteroidetes ratio was higher in men than females due to the overrepresentation of Firmicutes in men and overrepresentation of Bacteroidetes in case of females. Finally, Illumina MiSeq sequencing of 16S rRNA V4 region was allowing cheap and efficient studying of gut microbiota.
doi:10.21608/rpbs.2019.10975.1024 fatcat:foksg7wjr5hczn2mmy5idz6pnq