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Imaging axon regeneration within synthetic nerve conduits
2019
Scientific Reports
While axons within the central nervous system (CNS) do not regenerate following injury, those in the peripheral nervous system (PNS) do, although not in a clinically satisfactory manner as only a small proportion of axons exhibit long-distance regeneration. Moreover, functional recovery is hampered by excessive axonal sprouting and aberrant reinnervation of target tissue. In order to investigate the mechanisms governing the regrowth of axons following injury, previous studies have used lesion
doi:10.1038/s41598-019-46579-w
pmid:31300753
pmcid:PMC6626049
fatcat:i4zhzccaebca7cwlgvexyhnmhy