The vascular effects of a single bout of electronic cigarette use [article]

Ramon Eliseo Cossio
2018
As the use of electronic cigarettes (EC) begins to rise, the need to determine if they are indeed a safe alternative to traditional cigarettes (TC) is of utmost importance. As of 2016, over 15% of US adults age 18 or greater had tried electronic cigarettes. EC are commonly marketed as a safe alternative to TC, but recent studies have observed adverse effects on vascular functions from EC vapors similar to TC. Aim: To determine if EC vapor with 5.4% and 0% nicotine by volume have adverse effects
more » ... on key vascular functions in EC naïve subjects. Methods: 16 young apparently healthy subjects found to be free of cardiovascular and respiratory disease were recruited and screened to determine cigarette use. Each subject underwent three separate "vaping" trials with 5.4%, 0%, and sham EC. During each visit, endothelial function (via flow-mediated dilation) and arterial stiffness (via Cardio-Ankle Vascular Index) were measured at baseline, immediately post protocol, 1 hour post protocol (1hr), and 2 hours post protocol (2hr). A repeated measures ANOVA was used to determine if there were any significant time versus group interactions. Results: There were no significant changes in flow-mediated dilation (FMD), brachial blood vi pressure, and cardio ankle vascular index (CAVI) Score throughout the experiments lasting 2 hours. Conclusion: Vaping electronic cigarettes regardless of nicotine content are not significantly different from each other and do not produce lasting effects over the course of a 2-hour trial.
doi:10.15781/t2pz52578 fatcat:obgjyi6rqbaf3dmezdpw7l74ae