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Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls
2015
Statistics in Medicine
'Multistage testing with adaptive designs' was the title of an article by Peter Bauer that appeared 1989 in the German journal Biometrie und Informatik in Medizin und Biologie. The journal does not exist anymore but the methodology found widespread interest in the scientific community over the past 25 years. The use of such multistage adaptive designs raised many controversial discussions from the beginning on, especially after the publication by Bauer and Köhne 1994 in Biometrics: Broad
doi:10.1002/sim.6472
pmid:25778935
pmcid:PMC6680191
fatcat:kov3473tjjd6zp356lkb4hd23q