The Pfam Protein Families Database

A. Bateman
2000 Nucleic Acids Research  
Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the WWW in the UK at http://www.sanger.ac.uk/Software/Pfam/ , in Sweden at http://www.cgr.ki.se/Pfam/ and in the US at http:// pfam.wustl.edu/ . The latest version (4.3) of Pfam contains 1815 families. These Pfam families match 63% of proteins in SWISS-PROT 37 and TrEMBL 9. For complete genomes Pfam currently matches up to half of the proteins. Genomic DNA can be directly
more » ... rched against the Pfam library using the Wise2 package.
doi:10.1093/nar/28.1.263 pmid:10592242 pmcid:PMC102420 fatcat:qf5w6rqz3jh2tparq7622etwpm