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Developing a xenograft model of human vasculature in the mouse ear pinna
[article]
2019
biorxiv/medrxiv
pre-print
Humanised xenograft models allow for the analysis of human tissue within a physiological environment in vivo. However, current models often rely on the angiogenesis and ingrowth of recipient vasculature to perfuse tissues, preventing analysis of biological processes and diseases involving human blood vessels. This limits the effectiveness of xenografts in replicating human physiology and may lead to issues with translating findings into human research. We have designed a xenograft model of
doi:10.1101/789537
fatcat:b5c5nnsfcveord2xcy3idykoza