Endogenous opiates and fasting

A Ettenberg, J Rogers, G. Koob, F. Bloom, J. Deutsch
1981 Science  
Gambert et al. (1) claim to demonstrate decreases in the concentration of hypothalamic [-endorphin but not pituitary [-endorphin, hypothalamic adrenocorticotropin (ACTH), or pituitary ACTH in rat brain after a 3-day fast. From this they conclude that hypothalamic ,B-endorphin "may serve as a mechanism for the down-regulation of feeding behavior, enhancing energy conservation during periods of food storage." The authors, therefore, appear to assume that the correlational relation between
more » ... ion between hypothalamic 3-endorphin con-
doi:10.1126/science.6267697 pmid:6267697 fatcat:uss6katqlbal7bjtid6kmofile