Mutagenesis and immunological evaluation of group A streptococcal C5a peptidase as an antigen for vaccine development and as a carrier protein for glycoconjugate vaccine design

Hui Li, Subo Wang, Yisheng Zhao, Zonggang Chen, Guofeng Gu, Zhongwu Guo
2017 RSC Advances  
A non-enzymatic recombinant ScpA mutant (H193A) was prepared and investigated to probe its application potential in the development of GAS vaccines and as a carrier protein of glycoconjugate vaccines.
doi:10.1039/c7ra07923k fatcat:ofncsmn7ungwpikkj7dgniossi