Spock1 expression predicts prognosis in prostate cancer

Shao-Chuan Wang, Wen-Wei Sung, Chih-Jung Chen, Horng-Rong Chang
2016 Urological Science  
Purpose: Some studies reported a comparable oncological outcome and better early continence rate of Retzius-preserving robotic assisted laparoscopic radical prostatectomy (RALP). We want to compare the early perioperative and continence outcome. And we are also eager to know if the learning curve of Retzius-preserving surgery would compromise the outcome or not? Materials and Methods: We selected patient with organ-confined prostate cancer ( cT2c), PSA 40, Gleason score of biopsy 8, prostate
more » ... opsy 8, prostate volume 50 ml and BMI < 35. We design a case control matching study with 20 cases of each Retzius-preserving RALP and conventional RALP group. Postoperative parameter and early continence result was compared. Results: From Febuary, 2015 to Febuary, 2016, total 84 cases of RALP were performed in VGHTC. Twenty of them underwent Retzius-preserving RALP. There is no statistical difference of preoperative characteristics. There were no significant differences in estimated blood loss, mean length of hospital stay, intra-and postoperative complication rates, pathological stage of disease, Gleason scores, tumour volumes and positive surgical margins between the conventional RALP and Retzius-sparing RALP groups. However, console time, Vesicourethral anastomosis time were longer for Retzius-sparing RALP. There is no significant difference of early continence at 4 weeks between two groups. Conclusion: Based on the early result of this study, Retzius-preserving RALP is a feasible and safe treatment choice for localized prostate cancer. Both console time and anastomosis time are favoring to conventional RALP.
doi:10.1016/j.urols.2016.05.128 fatcat:cmpoyhf435ezhfuqw2rrr34ae4