Zonisamide for Attenuation of Weight Gain in a Morbidly-Obese Adolescent on an Antipsychotic

Mathew L. Nguyen, Michael A. Shapiroand
2012 Journal of Obesity & Weight Loss Therapy  
Obesity is a growing problem in the child and adolescent population. Particularly concerning is the trend of overweight children being increasingly prescribed antipsychotic medications that can lead to further weight gain. We present a case of a morbidly obese adolescent male who had made strides in weight loss with psychopharmacologic aide who was started on an antipsychotic. Weight loss plateaued, and zonisamide was added to further help with weight loss. We discuss the possible risks and
more » ... fits of this medication in aiding in preventing weight gain associated with antipsychotic medication. Volume 2 • Issue 4 • 1000134 J Obes Wt Loss Ther ISSN: 2165-7904 JOWT, an open access journal word-finding difficulties, and 3) somnolence or fatigue. In placebocontrolled trials, 2.2% of patients discontinued Zonegran or were hospitalized for depression compared to 0.4% of placebo patients, while 1.1% of Zonegran and 0.4% of placebo patients attempted suicide [9] ". This is particularly important in the child and adolescent population, especially given the FDA warning on Anti-Epileptic Drugs (AED) in patients aged 24 and younger [18]. Johnny did not experience any worsening aggression or agitation with the addition of the zonisamide.
doi:10.4172/2165-7904.1000134 fatcat:cxt6d2w3efafzc2fuoswavfqk4