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Pharmacological characterization of swelling-induced d-[3H]aspartate release from primary astrocyte cultures
1998
American Journal of Physiology - Cell Physiology
Rutledge, Eric M., Michael Aschner, and Harold K. Kimelberg. Pharmacological characterization of swellinginduced D-[ 3 H]aspartate release from primary astrocyte cultures. Am. J. Physiol. 274 (Cell Physiol. 43): C1511-C1520, 1998.-During stroke or head trauma, extracellular K ϩ concentration increases, which can cause astrocytes to swell. In vitro, such swelling causes astrocytes to release excitatory amino acids, which may contribute to excitotoxicity in vivo. Several putative
doi:10.1152/ajpcell.1998.274.6.c1511
fatcat:v4fyde6iurblhkdyucsd7xgwsu