Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences

Jang-Kyun Seo, Kazusato Ohshima, Hyeok-Geun Lee, Moonil Son, Hong-Soo Choi, Su-Heon Lee, Seong-Han Sohn, Kook-Hyung Kim
2009 Virology  
The complete genomes of 30 Soybean mosaic virus (SMV) isolates and strains were sequenced in this study. Together with fourteen previously reported sequences, we analyzed the genetic structure of the SMV population. Analyses of genetic diversity showed that different genomic regions of SMV are under different evolutionary constraints and that there was no significant genetic differentiation between East Asian and North American populations of SMV. Phylogenetic analyses revealed a significant
more » ... relation between phylogeny of the cylindrical inclusion (CI) gene of SMV and SMV resistance gene 3 (Rsv3)-relating pathogenicity of SMV, suggesting CI might be a pathogenic determinant in Rsv3-mediated disease response. Interestingly, recombination analyses identified 19 'clear' recombination events in the SMV population. Furthermore, as several resistance-breaking strains were identified as recombinants, it appears that recombination might contribute to overcome host resistance in SMV-soybean pathosystem. Our finding suggests that recombination as well as mutation is an important evolutionary process in the genetic diversification of SMV population.
doi:10.1016/j.virol.2009.07.007 pmid:19716150 fatcat:t5pi7hbi7zfudnfpyhwdue3gmy