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In the context of global change, emerging risks associated with parasites, inva-sive species and infectious diseases are an important issue especially for developing countries whose economies are resource-based. Our objective is to provide a mathematical framework to study the response of a harvested predator-prey system to a disease in the predator and proportional harvesting of predator. We combine a classical predator-prey model with an eco-epidemiological model where predator disease isfatcat:lhqxdq4j7vewphcqpibg4x6fjy