Field evaluation of near point of care Cepheid GeneXpert HIV-1 Qual for early infant diagnosis

Valarie Sarah Opollo, Alliance Nikuze, Jihane Ben-Farhat, Emily Anyango, Felix Humwa, Boaz Oyaro, Stephen Wanjala, Willis Omwoyo, Maxwel Majiwa, Victor Akelo, Clement Zeh, David Maman (+1 others)
2018 PLoS ONE  
Access to point-of-care HIV testing shortens turn-around times, time to diagnosis and reduces loss to follow-up hence minimizing barriers to early linkage to care and treatment among HIV infected infants. Currently samples for early infant HIV diagnosis are sent to centralized testing facilities which are few and located only at specific regions in Kenya. However, there are Point of Care (POC) early infant diagnosis [EID] technologies elsewhere such as SAMBA and ALERE-Q that are yet to be
more » ... ted in Kenya despite the urgent need for data to inform policy formulation regarding EID. The Cepheid GeneXpert HIV-1 Qual (GeneXpert) technology for POC EID offers a great opportunity to minimize HIV associated morbidity, mortality and loss to follow-up through decentralization of early infant HIV testing to the clinics. This technology also allows for same-day results thus facilitating prompt linkage to care.
doi:10.1371/journal.pone.0209778 pmid:30589900 pmcid:PMC6307732 fatcat:foa6pldc4jh5lihmdngvuz4y2u