Prevalence and Risk of Rupture of Intracranial Aneurysms

Gabriel J. E. Rinkel, Mamuka Djibuti, Ale Algra, J. van Gijn
1998 Stroke  
and Purpose-The estimates on the prevalence and the risk of rupture of intracranial saccular aneurysms vary widely between studies. We conducted a systematic review on prevalence and risk of rupture of intracranial aneurysms and classified the data according to study design, study population, and aneurysm characteristics. Methods-We searched for studies published between 1955 and 1996 by means of a MEDLINE search and a cumulative review of the reference lists of all relevant publications. Two
more » ... publications. Two authors independently assessed eligibility of all studies and extracted data on study design and on numbers and characteristics of patients and aneurysms. Results-For data on prevalence we found 23 studies, totalling 56 304 patients; 6685 (12%) of these patients were from 15 angiography studies. Prevalence was 0.4% (95% confidence interval, 0.4% to 0.5%) in retrospective autopsy studies, 3.6% (3.1 to 4.
doi:10.1161/01.str.29.1.251 pmid:9445359 fatcat:lmsqr6tmw5cnrahq4rgl5e3edq