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Development and Immunological Function of Lymph Node Stromal Cells
2021
Journal of Immunology
Stromal cells have for a long time been viewed as structural cells that support distinct compartments within lymphoid tissues and little more. Instead, an active cross-talk between endothelial and fibroblastic stromal cells drives the maturation of lymphoid niches, a relationship that is recapitulated during lymph node organogenesis, steady-state conditions, and following inflammation. In this review, we go over recent advances in genetic models and high-resolution transcriptomic analyses that
doi:10.4049/jimmunol.2000914
pmid:33397739
fatcat:bcvxkopzhnd7fafbyieppnt4mm