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MAPK pathway regulated the cardiomyocyte apoptosis in mice with post-infarction heart failure
2017
Bratislava Medical Journal
BACKGROUND: To explore the role of the MAPK signaling pathway in the cardiomyocyte apoptosis of mice with post-infarction heart failure (HF). METHODS: Mice were divided into sham and myocardial infarction (MI) groups. Before surgery, the MI group was divided into SB203580 and PBS subgroups. A post-infarction HF model was established by ligating the left anterior descending coronary artery. Ventricular dilatation and cardiac function were observed by small animal echocardiography. The growth of
doi:10.4149/bll_2017_065
pmid:28664743
fatcat:gkcptwon5vfypawtkxenyb67he