Oxidative Cross Coupling of sp3-C—H Bonds Catalyzed by Bu4NAuCl4with H2O2as Oxidant

Yan Zhang, Chengjian Zhu
2012 Youji huaxue  
Activation of two sp 3 -C-H bonds and oxidative alkylation of sp 3 -C-H bond adjacent to a nitrogen atom of tertiary amine were catalyzed by Bu 4 NAuCl 4 with H 2 O 2 as oxidant under mild reaction conditions. The safe, convenient, and environmentally benign process, as well as the broad substrate scope, low catalyst loading, high selectivity, short reaction time, and good yields make the protocol very practical.
doi:10.6023/cjoc201210029 fatcat:qwnmibgfcvblfdt7x3gdkqajky