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Iranian Journal of Pediatrics
Objective: Clonidine is an α2-agonist which is used as a sedative premedication in children. There are conflicting results in the published literature about the effect of clonidine on the incidence of post operative nausea and vomiting (PONV). We therefore decided to evaluate the effect of oral clonidine given preoperatively on the incidence of PONV in children after appendectomy. Methods: sixty children, 5-12 years old, classified as American Society of Anesthesiologists physical status I andfatcat:nbdtevrm6zexhmpnmaecdbwyuu