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There have been recent reports from various centres of a possible association between avascular necrosis of the jaws and the use of bisphosphonates. This commentary reviews the available data and alerts clinicians to a possible adverse reaction in the oral cavity to a group of drugs that are commonly prescribed. Ann Acad Med Singapore 2004;33(Suppl):48S-49Sfatcat:xvn25l6n7zdaziaezcaobwuori