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Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen
A small number of maternal effect genes determine anterior-posterior pattern in the Drosophila embryo. Embryos from females mutant for the maternal gene bicoid lack head and thorax. bcd mRNA becomes localized to the anterior tip of the egg during oogenesis and is the source for the morphogen gradient of bcd protein. Here we show that in vitro transcribed bicoid mRNA that has its own leader sequences substituted by the Xenopus beta-globin 5' untranslated sequences is translated more efficientlypmid:2226200 fatcat:2lwqvkfnmvajna4zm2a7m2etp4