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A 3D two-point method for whole-brain water content and relaxation time mapping: Comparison with gold standard methods
2018
PLoS ONE
Quantitative imaging of the human brain is of great interest in clinical research as it enables the identification of a range of MR biomarkers useful in diagnosis, treatment and prognosis of a wide spectrum of diseases. Here, a 3D two-point method for water content and relaxation time mapping is presented and compared to established gold standard methods. The method determines free water content, H2O, and the longitudinal relaxation time, T1, quantitatively from a two-point fit to the signal
doi:10.1371/journal.pone.0201013
pmid:30161125
pmcid:PMC6116981
fatcat:4arxag722faqzlkdwaggqmidsy