Synthetic insecticides are the main method of controlling vectors, but they haven't worked very well because the bugs have become resistant to them. Based on this, insecticides made from plants seem like a good choice for both man and the environment. Thus, the goal of the present work was to evaluate the effect of methyl triphenyl acetate (1-Propanone, 3-(2-hydroxyphenyl)-1,3-diphenyl)on 4 th instar larvae of Aedes aegypti by larvicidal, pupicidal and histopathological assays. The larvae and

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... pae were exposed to methyl triphenylacetate (MTA) at different concentrations viz. 3, 6, 9, 12 and 15 ppm for 72 hours. The larval LC50 and LC90 mortality rate was 4.68 ppm while LC90 values were 12.483 ppm; the pupa LC50 and LC90 mortality was 5.182 ppm, and LC90 value was 13.180 ppm MTA, respectively. Further, the histopathological analysis revealed that MTA treated larvae showed damaged midgut than control. The present findings presented that the MTA possess suitable insecticidal property against Aedes aegypti.