Reduction in thrombus formation by placement of endovascular stents at endarterectomy sites in baboon carotid arteries

W C Krupski, A Bass, A B Kelly, S R Hanson, L A Harker
1991 Circulation  
subsequent restenosis.1-'0 For example, acute coronary angioplasty undergoes thrombo-occlusion in about 4-5% of patients, and detectable restenosis occurs in up to 20% of patients1-3 undergoing carotid endarterectomy, and averages 30% after percutaneous transluminal coronary angioplasty.4-8 Although antithrombotic therapies with aspirin, dipyridamole, and heparin have decreased thrombo-occlusive events, they have not abolished these complications.9-14 Endovascular mechanical support, first
more » ... ted by Dotter15 in 1969, has been proposed as a means to reduce both acute and chronic vessel closure by providing a supporting framework for the disrupted and sometimes dissected arterial wall. To determine the effect of endovascular stents on thrombus formation induced by mechanically injured arterial flow surfaces, self-expanding stainless steel by guest on August 17, 2017 Downloaded from Root HD, Rogers W: Intraluminal stents in atherosclerotic iliac artery stenosis: Preliminary report of a multicenter study.
doi:10.1161/01.cir.84.4.1749 pmid:1914112 fatcat:yar4h64vdnbyli4qqwdgjmkb3e