A Study of the PDGF Signaling Pathway with PRISM

Qixia Yuan, Jun Pang, Sjouke Mauw, Panuwat Trairatphisan, Monique Wiesinger, Thomas Sauter
<span title="2011-09-08">2011</span> <i title="Open Publishing Association"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qzezkwolyvf33pglm2jldjklca" style="color: black;">Electronic Proceedings in Theoretical Computer Science</a> </i> &nbsp;
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway can be analyzed in PRISM. We show that quantitative verification can yield a better understanding of the PDGF signaling pathway.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4204/eptcs.67.7">doi:10.4204/eptcs.67.7</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pgl4iaqqlvbitjkfjd4a37kjhe">fatcat:pgl4iaqqlvbitjkfjd4a37kjhe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20160910162448/http://satoss.uni.lu/members/sjouke/papers/YPMTWS11.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fc/39/fc3924193bd83c843a230175c70f98b8c06b0c6d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4204/eptcs.67.7"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>