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Revisiting the role of the insula in addiction
2015
Trends in Cognitive Sciences
Brain lesions that damage the insular cortex interrupt addictive behaviors, suggesting that drug addiction sensitizes the insula. However, neuroimaging studies seem to lead to an opposite picture: structural neuroimaging studies show reduced grey matter volume of the insular cortex (IC) of drug users, and functional neuroimaging studies show reduced IC activity when drug users perform decision-making tasks. These results have been interpreted as indicating that addictive behaviors are
doi:10.1016/j.tics.2015.05.005
pmid:26066588
pmcid:PMC4486609
fatcat:qar2oydi5fad3nhxk3axjiojlu