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Dome formation by a retrovirus-induced lung adenocarcinoma cell line
1982
Cancer Research
A cell line has been established from an alveologenic lung adenocarcinoma that develops in newborn NFS/N mice after i.p. inoculation with a carcinoma-inducing retrovirus. A clonal derivative of this cell line, 3041, forms adenocarcinomas when injected into syngeneic weanling mice and in culture retains several properties typical of alveologenic type 1 cells. These include morphological details, such as tight junctions and interdigitating microvilli in the areas of cell-cell contact, as well as
pmid:6279287
fatcat:vrzzswqagbha7fcidxo5puxhcq