This study was conducted to determine the effects of hesperidin, a flavonoid added to quail rations, on blood serum, antioxidant enzymes in tissues, intestinal histomorphology and fecal microflora. In this context, three groups have been created. The first group has been administered basal ration (Group C). The second group (HES1) has been administered basal ration with hesperidin (1g / kg feed). The third group (HES2) has been administered basal ration with additional hesperidin (2g / kg

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... The experiment lasted 35 days. Blood, tissue and feces samples were taken at the end of the experiment. A significant difference has been found in the blood serum in terms of ALT, AST, LDH and Amylase enzymes in the groups with hesperidin compared to the control group (p < 0.05). A significant difference was found in the hesperidine groups in tissue antioxidant GSH, CAT and SOD enzyme parameters compared to the control group (p < 0.05). When looking at the intestinal histomorphology, a significant difference has been found within the test groups in the colon in terms of both villus height and crypt depth, and at villus height in the cecum tissue. As a result, the study's hypothesis has been supported by the fact that hesperidin positively affects the lipid concentration of quail, rump, liver and serum antioxidant enzyme levels, intestinal histomorphology and feces microflora of anaerobe bacteria, particularly Clostridium spp.