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Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a randomized, single-blind, crossover study

M. K. Mahende, E. Huber, E. Kourany-Lefoll, A. Ali, B. Hayward, D. Bezuidenhout, W. Bagchus, A. M. Kabanywanyi
2021

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Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans; however, the current tablet formulation is not suitable for pre-school age children mainly due to its bitterness and the large tablet size. We assessed the palatability of two new orally disintegrating tablet (ODT) formulations of PZQ.
doi:10.5451/unibas-ep89221 fatcat:alzb76e6gfbdjdojqlyfkjck64
Citation

M. K. Mahende, E. Huber, E. Kourany-Lefoll, A. Ali, B. Hayward, D. Bezuidenhout, W. Bagchus, A. M. Kabanywanyi. "Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a randomized, single-blind, crossover study." (2021)