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Objectives: Interictal epileptiform discharges (IEDs) have been linked to memory impairment, but the spatial and temporal dynamics of this relationship remain elusive. In the present study, we aim to systematically characterize the brain areas and times at which IEDs affect memory. Methods: Eighty epilepsy patients participated in a delayed free recall task while undergoing intracranial electroencephalography (EEG) monitoring. We analyzed the locations and timing of IEDs relative to thedoi:10.1111/epi.13633 pmid:27935031 pmcid:PMC5339047 fatcat:s7zv5vkx5rasxjqy7pjvyxqvte