A thromboembolic model for the efficacy and safety evaluation of combined mechanical and pharmacologic revascularization strategies

Matthew J Gounis, Raul G Nogueira, Manik Mehra, Juyu Chueh, Ajay K Wakhloo
2012 Journal of NeuroInterventional Surgery  
and purpose Recanalization strategies mediated by intra-arterial fibrinolytic therapy in combination with mechanical clot disruption may be a more effective treatment approach than either therapy used alone. There are few preclinical animal models to evaluate these strategies. Here we report on a model to simultaneously evaluate both of these treatment approaches.
doi:10.1136/neurintsurg-2012-010435 pmid:22962414 pmcid:PMC3623027 fatcat:tvwpgivfkbaivbhgmcbihuchge