Aqueous extract of Costus Specious ameliorates the toxic effect of lead acetate on transcriptional factors of erythropioesis

Yousef M. Shehata, Mohamed F. Dowidar, Haytham A. Ali, Aaser M. Abdelazim, Eman M. Elmogy
2014 Biochemistry Letters  
The increase use of medicinal plants during last 5 years encourages us to study the possible effects of Coustus Speciosus. Objective: In the present study, we tested the effect of Costus speciosus on the toxicity of Lead acetate. Results: The results showed an increase of EPO and high expression levels of GATA-1 and FOG-1 while there is a low expressional level of SCF in animals treated with Costus speciosus. Conclusion: Costus Specious has the ability to ameliorate the toxicity of lead acetate on erythropioesis.
doi:10.21608/blj.2014.63859 fatcat:u5bj5e2a6vfjrans3jmhonu6xu