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Endothelin-1 activates Homer 1α expression via mitogen-activated protein kinase in cardiac myocytes
International Journal of Molecular Medicine
Homer proteins are a family of scaffolding proteins which may play an important role in calcium signaling by facilitating the assembly of signaling complexes in neuronal cells. Among the three splice variants of Homer 1, Homer 1a is rapidly up-regulated by neural stimulation and may regulate the disassembly of signaling complexes mediated by Homer proteins. In spite of its potential importance in calcium signaling, the regulation of Homer 1a expression in cardiac myocytes has never beendoi:10.3892/ijmm.18.1.193 fatcat:hek52h4jurhh3li7qvgu6t77x4