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MUTATOR MUTATIONS IN BACTERIOPHAGE T4 GENE 42 (dHMC HYDROXYMETHYLASE)
Temperature-sensitive mutations of bacteriophage T4 gene 42 produce diverse effects upon spontaneous mutation rates. G:C → A:T transition rates are increased, often strongly; frameshift mutation rates are weakly increased; A:T → G:C transition rates (and perhaps also A:T → Py:Pu transversion rates) are decreased; and one G:C → Py:Pu transversion rate is also decreased. These results, together with certain interactions between gene-42 mutator effects and both base analogue mutagenesis and thedoi:10.1093/genetics/86.3.501 fatcat:gwto2rhluvhzlfdaiq7vpl4s5e