A Possible Treatment Strategy and Clinical Factors to Estimate the Treatment Response in Bebesia gibsoni Infection

Koretoki SUZUKI, Haruna WAKABAYASHI, Masashi TAKAHASHI, Kenjiro FUKUSHIMA, Akira YABUKI, Yasuyuki ENDO
2007 Journal of Veterinary Medical Science  
The effectiveness of combination therapy using clindamycin, metronidazole and doxycycline against canine babesiosis, and the usefulness of platelet count and the plasma C-reactive protein (CRP) concentration as an estimation factor for treatment, were evaluated in four dogs experimentally infected with Babesia gibsoni. The combination therapy successfully eliminated B. gibsoni in peripheral blood in 3 of 4 dogs, however the remaining dog showed obvious uncontrolled relapse after a temporary
more » ... very. In addition, it was shown that CRP levels decreased in an inverse relationship to the recovery of packed cell volume and therefore CRP levels could be used as an optional clinical marker to estimate the response to treatment. KEY WORDS: babesia, canine, treatment.
doi:10.1292/jvms.69.563 pmid:17551236 fatcat:v375hfmjovaupcofypqhf4n4ly