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Objective: To predict the immunogenic epitopes from human papillomavirus (HPV) virus using matrix based computational tools.Methods: In the present study, three matrix based algorithms, SYFPETHI, BIMAS and RANKPEP were used to predict the cytotoxic T lymphocyte (CTL) epitopes of HPV 16 and 18. The ability of the peptides to bind HLA A_0201, a most common allele, was evaluated using these algorithms. High scoring peptides were considered as potential binders.Results: Evaluation of HPV 16doi:10.22159/ijpps.2017v9i11.21523 fatcat:7ymomamu2jcdzk63zh5dyiecfy