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A fly's eye view of quiescent neural stem cells
Oxford Open Neuroscience
The balance between proliferation and quiescence of stem cells is crucial in maintaining tissue homeostasis. Neural stem cells (NSCs) in the brain have the ability to be reactivated from a reversible quiescent state to generate new neurons. However, how NSCs transit between quiescence and reactivation remains largely elusive. Drosophila larval brain NSCs, also known as neuroblasts, have emerged as an excellent in vivo model to study molecular mechanisms underlying NSC quiescence anddoi:10.1093/oons/kvac001 fatcat:v3hsntj46naqbm3vcdclh7h7ee