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AbstractIn a delayed alternation spatial working memory task, hippocampal time cells fire during specific moments of the delay period to form a stable, sequential representation of the entire delay interval. The causal relationship between these sequences and working memory remains unclear. Similarly, hippocampal theta oscillations are thought to support working memory, primarily through the generation of time cell sequences. To causally examine these relationships, we optogenetically silenceddoi:10.1101/2022.06.25.497592 fatcat:2km6l2f2cng63m6g5yk5c4qae4