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Transcriptome Analysis of Desquamative Interstitial Pneumonia (DIP)
Desquamative interstitial pneumonia (DIP) is a rare diffuse parenchymal lung disease of unclear etiology. A recent study showed that mice overexpressing Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) in lungs develop DIP-like disease, suggesting that pulmonary GM-CSF may be involved in the pathogenesis of DIP. To determine if GM-CSF is involved in human DIP lungs, we performed transcriptome analysis on human DIP lung tissue. We also extended transcriptome analysis to respiratorydoi:10.1101/791350 fatcat:gptnls2rnzgr5bhl5n3ingrtfm