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Machine Learning-Based Enzyme Engineering of PETase for Improved Efficiency in Degrading Non-Biodegradable Plastic
[article]
2022
bioRxiv
pre-print
Globally, nearly a million plastic bottles are produced every minute (1). These non-biodegradable plastic products are composed of Polyethylene terephthalate (PET). In 2016, researchers discovered PETase, an enzyme from the bacteria Ideonella sakaiensis which breaks down PET and nonbiodegradable plastic. However, PETase has low efficiency at high temperatures. In this project, we optimized the rate of PET degradation by PETase by designing new mutant enzymes which could break down PET much
doi:10.1101/2022.01.11.475766
fatcat:qemshcimxnbtdnrr5nc4iiaoki