Implementation of a high-sensitivity micro-angiographic fluoroscope (HS-MAF) for in-vivo endovascular image guided interventions (EIGI) and region-of-interest computed tomography (ROI-CT)

C. N. Ionita, C. Keleshis, V. Patel, G. Yadava, K. R. Hoffmann, D. R. Bednarek, A. Jain, S. Rudin, Kevin R. Cleary, Michael I. Miga
2008 Medical Imaging 2008: Visualization, Image-guided Procedures, and Modeling  
New advances in catheter technology and remote actuation for minimally invasive procedures are continuously increasing the demand for better x-ray imaging technology. The new x-ray highsensitivity Micro-Angiographic Fluoroscope (HS-MAF) detector offers high resolution and realtime image-guided capabilities which are unique when compared with commercially available detectors. This detector consists of a 300 μm CsI input phosphor coupled to a dual stage GEN2 micro-channel plate light image
more » ... fier (LII), followed by minifying fiber-optic taper coupled to a CCD chip. The HS-MAF detector image array is 1024×1024 pixels, with a 12 bit depth capable of imaging at 30 frames per second. The detector has a round field of view with 4 cm diameter and 35 microns pixels. The LII has a large variable gain which allows usage of the detector at very low exposures characteristic of fluoroscopic ranges while maintaining very good image quality. The custom acquisition program allows real-time image display and data storage. We designed a set of in-vivo experimental interventions in which placement of specially designed endovascular stents were evaluated with the new detector and with a standard x-ray image intensifier (XII). Capabilities such fluoroscopy, angiography and ROI-CT reconstruction using rotational angiography data were implemented and verified. The images obtained during interventions under radiographic control with the HS-MAF detector were superior to those with the XII. In general, the device feature markers, the device structures, and the vessel geometry were better identified with the new detector. High-resolution detectors such as HS-MAF can vastly improve the accuracy of localization and tracking of devices such stents or catheters. Keyword list high-resolution fluoroscopy; cone-beam computed tomography; region-of-interest microangiography; ROI-CT; endovascular image-guided interventions; micro-angiographic fluoroscope
doi:10.1117/12.770297 pmid:18958294 pmcid:PMC2572822 dblp:conf/miigp/IonitaKPYHBJR08 fatcat:l5w7hxhcqfgbngvkjlwiudzcpm