EAACI Molecular Allergology User's Guide

P. M. Matricardi, J. Kleine-Tebbe, H. J. Hoffmann, R. Valenta, C. Hilger, S. Hofmaier, R. C. Aalberse, I. Agache, R. Asero, B. Ballmer-Weber, D. Barber, K. Beyer (+53 others)
2016 Pediatric Allergy and Immunology  
The European Academy of Allergy and Clinical Immunology, EAACI, is a non-profit organisation active in the field of allergic and immunologic diseases such as asthma, rhinitis, eczema, occupational allergy, food and drug allergy and anaphylaxis. EAACI was founded in 1956 in Florence and has become the largest medical association in Europe in the field of allergy and clinical immunology. It includes over 9300 members from 121 countries, as well as 54 National Allergy Societies. This book contains
more » ... information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish realiable data and information, but the authors and the publisher make no representations or warranties with respect to, nor assume responsibility for, the validity or accuracy of all materials or the consequences of their use and shall not be liable for any damages arising from reliance thereon. If professional advice or other expert assistance is required, the services of a competent professional should be sought. D02 375 Glossary of Immunological Assays in Molecular Allergology D03 379 Abbreviations and Acronyms D04 383 Acknowledgements PREFACE FROM THE EAACI PRESIDENT EAACI MOLECULAR ALLERGOLOGY USER'S GUIDE Allergic diseases are still steadily rising and affecting a large number of individuals who are also facing an overall worsening of their clinical manifestations at any point during their life-time. Many children suffer from severe food allergy and anaphylaxis, many adolescents and young adults are underperforming due to asthma and allergic rhinitis and many adults are missing work due to co-morbidities of allergic diseases. Allergy is currently a public health issue although hugely underestimated and under -recognized. There is a need to improve the care of allergic patients through better education of health professionals and the public. As part of its Mission the European Academy of Allergy and Clinical Immunology -EAACI has started a project aimed to translate best knowledge into best practice. Atlases and Guidelines represent a comprehensive set of documents that are distributed for improving appraisal and proper management of allergy. This User's Guide for Molecular Allergology will be another breakthrough in this regard. Recombinant technology in the field of allergology has brought tremendous advances in allergen characterization as well as in the knowledge of immune mechanisms involved in allergic diseases. Molecular allergology takes diagnostics one-step further. It can enable you to get better perspectives on the risk connected with sensitization. Sensitization to the components is measured individually helping to pinpoint on an exact molecular level which component the patient is sensitized to. In light of this, allergen extracts are being step-by-step replaced by molecule-based products. The new developments will allow clinicians to obtain detailed information on sensitization patterns and more accurate interpretation of allergic symptoms. This information provides the basis for a refined , earlier , diagnosis of the allergic reactions and ultimately for a tailored individualized management of the patient, including opportunities for prevention. In this regard, molecular allergology is a further, excellent example of how allergy is linked to precision medicine and drives precision health forward. Moreover, this book is also the culmination of the EAACI spirit of team working. It comes from an outstanding effort from many: the EAACI Board of Officers, the Executive Committee and the 100 contributors who have volunteered in this activity to get it finalized. Without their enthusiasm and continuous support this achievement would not have been accomplished.
doi:10.1111/pai.12563 pmid:27288833 fatcat:u64c6gm5enhj7h6g4r5xddnk6u